Ganoderma and Health : Biology, Chemistry and Industry & Pharmacology and Clinical Application

Publication date / 22 Nov 2019 & 10 Jan 2020
Author & Editors / Zhibin Lin, Baoxue Yang
Publisher / Springer Verlag, Singapore
Language / English  ISBN / 9789811398667 & 9789813294202
Dimensions / 155 x 235  Format / 204 pages & 321 pages
About this book / Presenting a state-of-the-art report on recent advances concerning Ganoderma. Focusing on advances made over the past 20 years in the research history, classification, chemical components and industry of Ganoderma. Offering new insights into development and clinical application of Ganoderma and related products.

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About this book|關於本書

This book presents a state-of-the-art report on recent advances concerning Ganoderma and where the field is going. Although some older work is also cited, the main focus is on advances made over the past 20 years in the pharmacology and clinical applications of Ganoderma.

Ganoderma lucidum (Lingzhi) has been used as a traditional medicine in Asian countries to maintain health and to treat diseases for more than two thousand years. Recently, its value has been demonstrated in preventing and treating certain diseases, such as tumors, liver disorders, renal injury, hypercholesterolemia, obesity, cerebral ischemia reperfusion, bronchitis etc.

In addition, laboratory and clinical studies have confirmed that the chemical components of Ganoderma, such as Ganoderma lucidum polysaccharide peptides and triterpenes isolated from the fruiting body of Ganoderma lucidum, produce diverse pharmacological effects.

Ganoderma and its components play an important part in antioxidant stress, radical-scavenging, immunomodulation, and intracellular signaling regulation, and accordingly warrant further study.

This book systematically reviews the latest advances in our understanding of pharmacology and clinical applications of Ganoderma, and offers researchers and graduate students valuable new insights into the pharmacology and clinical applications of Ganoderma and related products.

由北京大學基礎醫學院林志彬教授和楊寶學教授共同主編的《Ganoderma and Health》(靈芝與健康,上下冊)一書已由Springer出版社於2019年11月正式出版發行。

該書上冊(Biology, Chemistry and Industry,生物學、化學和產業)系統介紹了靈芝的分類學、生物學特性、人工栽培、化學成分和產業的研究進展;下冊(Pharmacology and Clinical Application,藥理學和臨床應用)總結了靈芝及其提取物的藥理學研究進展和臨床應用。

靈芝作為一種傳統中藥,在我國已被用於養生保健和治療疾病兩千多年。近年來,靈芝人工培育技術促進了靈芝品種的優化、活性化合物的分離與鑒定,靈芝及其提取物相關產品的研發的發展。

實驗室和臨床研究也發現靈芝分離得到的靈芝多糖肽和三萜類化合物具有多種藥理作用。靈芝在治療腫瘤、肝臟疾病、腎損傷、高膽固醇血症、肥胖、腦缺血再灌注、支氣管炎等疾病方面的價值已得到證實。靈芝及其組分在抗氧化應激、自由基清除、免疫調節和細胞內信號調節中發揮重要作用。

本書將為靈芝學界的研究人員、產業界的研發人員和廣大消費者提供靈芝及其提取物相關產品的藥理學和臨床應用有價值的科學數據。

 

About the authors|關於編著者

Dr. Zhibin Lin(林志彬) is a Professor at the Department of Pharmacology, Peking University. He is also the honorary President of the Chinese Pharmacological Society, Senior Counsellor of the China Edible Fungi Association, and Councilor of the Southeast Asia Pacific Regional Federation of Pharmacologists.

Prof. Lin has been engaged in pharmacological research on Ganoderma for more than 40 years, and has also has been involved in the research, development and clinical applications of various Ganoderma products. He has published more than 100 research articles on the topic.

林志彬教授,1961年畢業於北京醫學院醫療系;曾任北京大學基礎醫學院副院長兼基礎醫學研究所所長、藥理學系主任,北京醫科大學副校長;美國伊利諾伊大學訪問學者;俄羅斯彼爾姆藥學研究院名譽教授;香港大學訪問教授;國際臨床和基礎藥理學聯合會(IUPHAR)執行委員;中國藥理學會理事長等。現任中國中藥協會靈芝專業委員會名譽主任委員。

長期從事抗炎症藥、免疫調節藥、抗腫瘤藥的藥理作用和作用機制研究,採用現代科技方法研究傳統中藥靈芝及其有效成分的免疫調節作用、抗腫瘤作用、保肝作用、抗糖尿病作用,取得重要成果。連續五年(2014-2018)入選愛思唯爾中國高被引用學者榜單。獲靈芝授權專利5項。

 

Dr. Baoxue Yang(楊寶學)is Vice Dean of the School of Basic Medical Sciences, and a Professor and Director of the Department of Pharmacology, Peking University. He is an executive committee member of the Chinese Pharmacological Society and chairman of the Chinese Pharmacological Society’s Nephropharmacology Division.

He is also chairman of the Lucid Ganoderma Division, China Association of Traditional Chinese Medicine. Prof. Yang’s research focuses on drug discovery, nephropharmacology and medicinal use of Ganoderma lucidum. He has published more than 160 articles in these fields and holds seven patents.

楊寶學教授,現任北京大學基礎醫學院副院長、藥理學系主任、教授、博士生導師。兼任天然藥物及仿生藥物國家重點實驗室研究員;中國藥理學會常務理事、中國藥理學會腎髒藥理專業委員會主任委員、北京藥理學會副理事長、中國中藥協會靈芝專業委員會主任委員、《中國藥理通訊》主編、《生理學研究》主編、《國際藥理學研究》副主編等。

主要研究領域為腎髒藥理學、靈芝及其提取物的藥理學、新藥發現與藥效學評價。在研項目包括國家自然科學基金重點項目、國家自然科學基金重點國際合作項目、NSFC/RGC聯合科研基金項目、科技部國際科技合作專項、北京自然科學基金等多項研究課題。已發表SCI論文127篇,連續五年(2014-2018)入選愛思唯爾中國高被引用學者榜單。獲授權專利7項。

 

Table of contents

Ganoderma and Health : Biology, Chemistry and Industry  (7 chapters)

1. Ganoderma (Lingzhi) in Traditional Chinese Medicine and Chinese Culture

2. Classification, Biological Characteristics and Cultivations of Ganoderma

3. Chemical Components of Ganoderma

4. Polysaccharide of Ganoderma and Its Bioactivities

5. Quantitative Analysis of Components in Ganoderma

6. Researches and Application of Ganoderma Spores Powder

7. Development and Innovation of Ganoderma Industry and Products in China

 

Ganoderma and Health : Pharmacology and Clinical Application (14 chapters)

1. Immunomodulating Effect of Ganoderma (Lingzhi) and Possible Mechanism

2. Antitumor Effect of Ganoderma (Lingzhi) Mediated by Immunological  Mechanism and Its Clinical Application

3. Cellular and Molecular Mechanism of Ganoderma (Lingzhi) Against Tumor

4. Protective Effect of Ganoderma (Lingzhi) on Radiation and Chemotherapy

5. Neuropharmacological Effect and Clinical Applications of Ganoderma (Lingzhi)

6. Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Brain Injury

7. Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System

8. Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Diabetes

9. Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Liver Injury

10. Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Renal Diseases and Clinical Applications

11. Anti-osteoporosis Effect of Ganoderma (Lingzhi) by Inhibition of Osteoclastogenesis

12. Antioxidative and Free Radical Scavenging Activity of Ganoderma (Lingzhi)

13. Anti-aging Effect of Ganoderma (Lingzhi) with Health and Fitness

14. Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Skin Diseases and Care

 

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