Hypercholesterolemia(中譯:高膽固醇血症)

出版日/2015年9月17日        
主    編/Sekar Ashok Kumar        
出版者/InTech        
語    言/英文        
版   本/電子版(開放線上閱讀)        
簡介/本書主要在介紹「高膽固血症」患者如何透過飲食與藥物防範動脈粥狀化引起的心血管疾病。其中由馬來西亞醫學研究所Choong Yew Keong博士撰寫的的〈第七章〉,詳細介紹了靈芝對高膽固醇血症的藥理功效、作用機制和活性成分,以及靈芝降血壓、抗氧化、保肝等作用在其中扮演的角色。作者並在結論中指出,雖然科學上還有一些細節需要釐清,但成分多元的靈芝萃取物肯定不會有有單一藥物那般副作用。

 

201509Hypercholesterolemia 
ISBN 978-953-51-2169-5

 

全書線上閱讀:Hypercholesterolemia

第七章 線上閱讀:Medicinal Values of Selected Mushrooms with Special Reference to Anti-Hypercholesterolemia

 

Chapter 7 Contents
Medicinal Values of Selected Mushrooms with Special Reference to Anti-Hypercholesterolemia 

1. Introduction(簡介)

1.1. HYPERCHOLESTEROLEMIA(高膽固醇血症)

1.1.1. RELATION OF HYPERCHOLESTEROLEMIA WITH ATHEROSCLEROSIS(高膽固醇血症與動脈粥狀硬化的關係)
1.1.2. MUSHROOMS AS MEDICINAL-FUNCTIONAL FOOD AGAINST HYPERCHOLESTEROLEMIA(對於高膽固醇血症有醫療功效的食材 ── 菇類)

 

2. Selective mushrooms as anti-hypercholesterolemia agent(力抗高膽固醇血症的食藥用菇)

2.1. GANODERMA POLYSACCHARIDES(靈芝多醣)

2.2. GANODERMA TRITERPENES(靈芝三萜)

3. Mechanism on different biomedical application of Ganoderma lucidum(靈芝不同活性成分的作用機制)

3.1. MECHANISM OF INHIBITORY EFFECT OF GANODERIC ACID ON HMG-COA REDUCTASE(靈芝酸對HMG-COA還原酶的抑制)

3.1.1. MECHANISM(作用機制)
3.1.2. COMPARISON OF STRUCTURE OF STATINS AND GANODERIC ACID DERIVATIVES(比較STATIN藥物和靈芝酸衍生物的化學結構)

3.2. MECHANISM AS ANGIOTENSIN CONVERTING ENZYME INHIBITOR IN RENIN ANGIOTENSION-ALDOSTERONE SYSTEM(靈芝抑制血管收縮素轉化酶的作用機制)

3.2.1. MECHANISM OF RENIN-ANGIOTENSIN SYSTEM (RAS) OF G. LUCIDUM EXTRACT(靈芝萃取物在腎素-血管收縮素系統的作用機制)
3.2.2. ACE INHIBITOR(血管收縮素轉化抑制劑)
3.2.3. COMPARATIVE STRUCTURE OF ACE INHIBITOR CAPTOPRIL AND GANODERIC ACID F(比較血管收縮素轉化抑制劑CAPTOPRIL和靈芝酸F的化學結構)

3.3. MECHANISM OF INHIBITION OF OXIDATIVE DAMAGE(靈芝抑制氧化損傷的機制)

3.3.1. THE MECHANISM OF SCAVENGING DPPH RADICALS(靈芝清除DPPH自由基的機制)3.3.2. INHIBITION OF LIPID PEROXIDATION (LPO)(靈芝對脂質過氧化反應的抑制作用)
3.3.3. REDUCING POWER(靈芝對氧化作用的還原能力)
3.3.4. CHELATING ABILITY ON FERROUS IONS(螯合亞鐵離子的能力)

3.4. MECHANISM OF INFLAMMATION — HEPATOPROTECTIVE EFFECT(靈芝的保肝作用)

3.4.1. MECHANISM OF HEPATOPROTECTIVE EFFECT OF GANODERMA EXTRACT(靈芝萃取物的保肝作用與機制) 

3.5. MECHANISM ON IMMUNOSTIMULATION WITH GANODERMA POLYSACCHARIDES(靈芝多醣的免疫調節機制)

3.6. MECHANISM — GANODERMA LANOSTANE-TYPE TRITERPENES AS POTENT FARNESOID-X-RECEPTOR (FXR) AGONISTS(靈芝羊毛固烷型三萜類調控FXR受體)

3.6.1. COMPARATIVE MOLECULAR STRUCTURE OF ACTIVE LANOSTANES AND CDCA(比較FXR標靶藥物CDCA與活性羊毛型三萜類的分子結構)
3.6.2. MECHANISM(作用機制)

4. Conclusion(總結)